Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 19/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 15/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24030791 | 0.95 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24030793 | 0.93 | HDAC6 (0.63) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24031068 | 0.93 | HDAC6 (0.74) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24031013 | 0.90 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24030789 | 0.90 | HDAC1 (0.59) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24031086 | 0.88 | HDAC6 (0.71) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL30317682 | 0.88 | HDAC6 (0.71) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24031112 | 0.87 | HDAC6 (0.72) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24247614 | 0.85 | HDAC6 (0.58) | HDAC6HDAC1HDAC8HDAC11HDAC2 | |
| SCHEMBL24031093 | 0.85 | HDAC6 (0.65) | HDAC6HDAC1HDAC8HDAC11HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-A | Histone Deacetylase (HDACS) inhibitors | 安基生技新药股份有限公司 | 2019-12-27 | — | — | CN | claimed |
| US-11535598-B2 | Histone deacetylases (HDACs) inhibitors | Annji Pharmaceutical Co., Ltd. (TW) | 2022-12-27 | — | — | US | disclosed |
| US-11535598-B2 | Histone deacetylases (HDACs) inhibitors | Annji Pharmaceutical Co., Ltd. (TW) | 2022-12-27 | — | — | US | disclosed |
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | disclosed |
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | disclosed |
| US-20210355089-A1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2021-11-18 | — | — | US | disclosed |
| CN-110621317-A | Histone Deacetylase (HDACS) inhibitors | 安基生技新药股份有限公司 | 2019-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535598-B2 | Histone deacetylases (HDACs) inhibitors | HDAC1, HDAC3, HDAC2 | HDAC6 11/4885HDAC1 1/4885HDAC8 6/4885 |
| US-20210355089-A1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | HDAC1, HDAC3, HDAC2 | HDAC6 8/4885HDAC1 1/4885HDAC8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.