Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 17/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.71 |
| ▸ | MELK | Q14680 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031086 | 1.00 | HDAC6 (0.71) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030751 | 0.94 | HDAC6 (0.70) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030736 | 0.92 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031112 | 0.91 | HDAC6 (0.72) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317751 | 0.89 | HDAC1 (0.73) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031013 | 0.89 | HDAC6 (0.62) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031069 | 0.89 | HDAC1 (0.73) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24031012 | 0.88 | PGR (0.57) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL30317687 | 0.88 | PGR (0.57) | HDAC6HDAC1HDAC8HDAC11MELK | |
| SCHEMBL24030792 | 0.88 | HDAC6 (0.63) | HDAC6HDAC1HDAC8HDAC11MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621317-B | Inhibitors of Histone Deacetylase (HDACS) | 安基生技新药股份有限公司 | 2023-05-12 | — | — | CN | disclosed |