Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21816596 | 0.83 | CA14 (0.35) | CCR5CA14 | |
| SCHEMBL3247076 | 0.73 | CA14 (0.34) | CCR5CA12CA1CA2CA14 | |
| SCHEMBL17184655 | 0.73 | CA12 (0.36) | CCR5CA12CA1CA2CA14 | |
| SCHEMBL21816632 | 0.71 | CA14 (0.36) | CCR5CA12CA1CA14 | |
| SCHEMBL2420804 | 0.70 | DPP4 (0.36) | CCR5CA14 | |
| SCHEMBL4717930 | 0.69 | HDAC6 (0.33) | CCR5CA14 | |
| SCHEMBL14876811 | 0.69 | EPHX1 (0.35) | CCR5 | |
| SCHEMBL21176718 | 0.68 | ANPEP (0.35) | CCR5 | |
| SCHEMBL3824368 | 0.68 | CCR5 (0.42) | CCR5 | |
| SCHEMBL21871393 | 0.68 | CA14 (0.36) | CA12CA1CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231571-A1 | HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE | CHDI FOUNDATION, INC. (US) | 2021-11-18 | — | — | WO | disclosed |