Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 7/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24033578 | 1.00 | EPHX1 (0.44) | EPHX1GAACYP2D6EPHX2MLYCD | |
| SCHEMBL1204076 | 0.83 | EPHX2 (0.47) | EPHX1EPHX2GLAHPGDATM | |
| SCHEMBL27704751 | 0.82 | EPHX1 (0.41) | EPHX1GAAEPHX2HDAC4HDAC1 | |
| SCHEMBL27685793 | 0.82 | EPHX1 (0.41) | EPHX1GAAEPHX2HDAC4HDAC1 | |
| SCHEMBL24033564 | 0.82 | EPHX1 (0.41) | EPHX1GAACYP2D6EPHX2HDAC4 | |
| SCHEMBL24034131 | 0.82 | EPHX1 (0.41) | EPHX1GAACYP2D6EPHX2HDAC4 | |
| SCHEMBL19744864 | 0.82 | EPHX1 (0.43) | EPHX1GAACYP2D6EPHX2HDAC4 | |
| SCHEMBL10825239 | 0.82 | EPHX1 (0.43) | EPHX1GAACYP2D6EPHX2HDAC4 | |
| SCHEMBL1204052 | 0.82 | EPHX2 (0.45) | EPHX1GAAEPHX2HPGDATM | |
| SCHEMBL26529447 | 0.81 | EPHX1 (0.41) | EPHX1CYP2D6EPHX2HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231892-A1 | CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF | ALGEN BIOTECHNOLOGIES, INC. (US) | 2021-11-18 | — | — | WO | disclosed |