Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.54 |
| ▸ | MET | P08581 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393055 | 0.90 | MET (0.49) | HRH3METKCNH2ALKOPRD1 | |
| SCHEMBL12392796 | 0.90 | MET (0.49) | HRH3METKCNH2ALKOPRD1 | |
| SCHEMBL12393052 | 0.87 | HRH3 (0.46) | HRH3METKCNH2OPRD1 | |
| SCHEMBL12392794 | 0.87 | HRH3 (0.46) | HRH3METKCNH2OPRD1 | |
| SCHEMBL2343518 | 0.86 | HRH3 (0.60) | HRH3METKCNH2ALK | |
| SCHEMBL2343522 | 0.86 | HRH3 (0.60) | HRH3METKCNH2ALK | |
| Trifluoroacetic Acid SCHEMBL2352536 | 0.86 | HRH3 (0.55) | HRH3METKCNH2ALK | |
| Trifluoroacetic Acid SCHEMBL2352539 | 0.86 | HRH3 (0.55) | HRH3METKCNH2ALK | |
| SCHEMBL2345178 | 0.84 | HRH3 (0.52) | HRH3METKCNH2OPRD1 | |
| SCHEMBL2345183 | 0.84 | HRH3 (0.52) | HRH3METKCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4777974-B2 | — | — | 2011-09-21 | — | — | JP | claimed |
| JP-2007530698-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1735278-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005097740-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-10-20 | — | — | WO | claimed |