SCHEMBL24035010

SCHEMBL24035010

c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccc3c(c2)c2cccc4c2n3c2cccc3c5cc([Si](c6ccccc6)(c6ccccc6)c6ccccc6)ccc5n(c5cccc6c7cc([Si](c8ccccc8)(c8ccccc8)c8ccccc8)ccc7n4c65)c32)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.31
FTO Q9C0B1 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24035023 0.98 KDM4E (0.34) MEN1MAPTKMT2AKDM4EGAA
SCHEMBL24035024 0.98 KDM4E (0.34) MEN1MAPTKMT2AKDM4EGAA
SCHEMBL24034882 0.95 MEN1 (0.30) MEN1MAPTKMT2AKDM4EGAA
SCHEMBL24034961 0.94 KDM4E (0.32) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL24034962 0.94 KDM4E (0.32) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL24034964 0.94 KDM4E (0.32) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL10153451 0.94 KDM4E (0.38) MEN1MAPTKMT2AKDM4EGAA
SCHEMBL10153509 0.94 KDM4E (0.38) MEN1MAPTKMT2AKDM4EGAA
SCHEMBL24034984 0.92 TSPO (0.36) MEN1MAPTKMT2AKDM4EALDH1A1
SCHEMBL24034954 0.89 KDM4E (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210355092-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355092-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXA1L MEN1 3437/4885MAPT 2153/4885KMT2A 3960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.