Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036289 | 0.88 | CYP2D6 (0.38) | MAPTKMT2AMEN1LMNA | |
| SCHEMBL24035319 | 0.87 | HDAC1 (0.38) | MAPTKMT2AMEN1LMNAHDAC1 | |
| SCHEMBL24035988 | 0.87 | MAPT (0.41) | MAPTLMNAHDAC1HDAC2 | |
| SCHEMBL24035941 | 0.87 | MAPT (0.37) | MAPTKMT2AMEN1LMNATP53 | |
| SCHEMBL24036170 | 0.86 | HDAC4 (0.44) | MAPTHDAC1HDAC2TP53 | |
| SCHEMBL24036171 | 0.86 | HDAC1 (0.41) | MAPTKMT2AMEN1LMNAHDAC1 | |
| SCHEMBL24035881 | 0.85 | LMNA (0.43) | MAPTKMT2ALMNATP53 | |
| SCHEMBL24852874 | 0.85 | MAPT (0.37) | MAPTKMT2AMEN1LMNAHDAC1 | |
| SCHEMBL24036294 | 0.85 | MAPT (0.40) | MAPTKMT2ALMNAHDAC1HDAC2 | |
| SCHEMBL24035160 | 0.85 | HDAC1 (0.35) | MAPTKMT2AMEN1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231474-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |