SCHEMBL2403785

SCHEMBL2403785

CC(C)=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194506 1.00
Charcoal, Activated SCHEMBL31423781 0.95
Trimethylammonium SCHEMBL27522747 0.87
SCHEMBL27695844 0.83
Methyl Alcohol SCHEMBL27801280 0.80
SCHEMBL28941779 0.78 LMNA (0.31)
SCHEMBL28958957 0.74
SCHEMBL1862942 0.74
SCHEMBL9527000 0.70
SCHEMBL28428063 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0966456-B1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF UNIV NEW YORK STATE RES FOUND (US) 2003-04-02 EP claimed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US claimed
US-11203583-B2 Prodrug and profluorescent compounds for selective mitochondrial imaging and therapeutic targeting ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-12-21 US disclosed
US-20200247775-A1 PRODRUG AND PROFLUORESCENT COMPOUNDS FOR SELECTIVE MITOCHONDRIAL IMAGING AND THERAPEUTIC TARGETING ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-08-06 US disclosed
US-10604501-B2 Prodrug and profluorescent compounds for selective mitochondrial imaging and therapeutic targeting ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-03-31 US disclosed
US-20190330176-A1 PRODRUG AND PROFLUORESCENT COMPOUNDS FOR SELECTIVE MITOCHONDRIAL IMAGING AND THERAPEUTIC TARGETING ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-10-31 US disclosed
US-20110212986-A1 ANTI-FLAVIVIRUS THERAPEUTIC HEALTH RESEARCH, INC. (US) 2011-09-01 US disclosed
WO-2010022238-A2 ANTI-FLAVIVIRUS THERAPEUTIC HEALTH RESEARCH, INC. (US) 2010-02-25 WO disclosed
EP-1497276-B1 CONVERSION OF TAXANE MOLECULES NATURAL PHARMACEUTICALS INC (US) 2008-08-20 EP disclosed
US-7220872-B2 Conversion of taxane molecules NATURAL PHARMACEUTICALS, INC. (US) 2007-05-22 US disclosed
US-7176325-B2 Selective acylation of secondary hydroxyl groups NATURAL PHARMACEUTICALS, INC. (US) 2007-02-13 US disclosed
US-20050234249-A1 Conversion of taxane molecules PHYTON HOLDINGS, LLC 2005-10-20 US disclosed
US-20050176975-A1 Selective acylation of secondary hydroxyl groups PHYTON HOLDINGS, LLC 2005-08-11 US disclosed
CN-1450997-A Inhibitors of copper-containing amine oxidases BIOTIE THERAPIES CORP (FI) 2003-10-22 CN disclosed
EP-0966456-B1 TAXOID REVERSAL AGENTS FOR DRUG-RESISTANCE IN CANCER CHEMOTHERAPY AND PHARMACEUTICAL COMPOSITIONS THEREOF UNIV NEW YORK STATE RES FOUND (US) 2003-04-02 EP disclosed
EP-1230225-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-08-14 EP disclosed
WO-2001032632-A2 PHARMACEUTICALLY ACTIVE 4-SUBSTITUTED PYRIMIDINE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-05-10 WO disclosed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US disclosed