Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24408437 | 0.84 | CYP11B2 (0.50) | CYP11B2CYP11B1GABRG2GABRB3GABRA5 | |
| SCHEMBL21754246 | 0.84 | CYP11B2 (0.50) | CYP11B2CYP11B1GABRG2GABRB3GABRA5 | |
| SCHEMBL12436807 | 0.84 | CYP11B2 (0.50) | CYP11B2CYP11B1GABRG2GABRB3GABRA5 | |
| SCHEMBL31403074 | 0.84 | ESR2 (0.58) | CYP11B2IDO1CYP11B1TAAR1ESR2 | |
| SCHEMBL4874 | 0.84 | CYP11B2 (0.54) | CYP11B2IDO1CYP11B1TAAR1ESR2 | |
| SCHEMBL18251131 | 0.84 | CYP11B2 (0.46) | CYP11B2IDO1CYP11B1TAAR1CYP17A1 | |
| SCHEMBL17941551 | 0.84 | ESR2 (0.58) | CYP11B2IDO1CYP11B1TAAR1ESR2 | |
| SCHEMBL13036070 | 0.84 | GRIN1 (0.52) | CYP11B2IDO1CYP11B1BACE1 | |
| SCHEMBL14784197 | 0.84 | TAAR1 (0.58) | CYP11B2IDO1CYP11B1TAAR1ESR2 | |
| SCHEMBL26923563 | 0.84 | MEN1 (0.59) | CYP11B2CYP11B1TAAR1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186571-B2 | Quinazolinone derivatives useful for imaging | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2021-11-30 | — | — | US | disclosed |
| WO-2021229302-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11186571-B2 | Quinazolinone derivatives useful for imaging | TNNI3, KLK3, BRDT | CYP11B2 242/4885IDO1 1223/4885CYP11B1 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.