Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900142 | 0.79 | ALDH1A1 (0.42) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL3401332 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL18463822 | 0.76 | — | — | |
| SCHEMBL20808343 | 0.76 | — | — | |
| SCHEMBL14679559 | 0.75 | — | — | |
| SCHEMBL13794277 | 0.75 | — | — | |
| SCHEMBL14039733 | 0.75 | — | — | |
| SCHEMBL13955565 | 0.73 | ALDH1A1 (0.48) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL18622132 | 0.71 | ALDH1A1 (0.41) | ALDH1A1ALOX15RECQLHSD17B10TSHR | |
| SCHEMBL14211575 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229302-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-11-18 | — | — | WO | disclosed |