Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838574 | 0.84 | ALDH1A1 (0.40) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL14829667 | 0.84 | ALDH1A1 (0.40) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL2655937 | 0.82 | ALDH1A1 (0.57) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL2056117 | 0.82 | HDAC3 (0.49) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL20746766 | 0.81 | HDAC3 (0.38) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL14829732 | 0.81 | HDAC1 (0.38) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL15120098 | 0.81 | HDAC1 (0.38) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL2655936 | 0.80 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL21698575 | 0.80 | HDAC3 (0.37) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL1956844 | 0.79 | HDAC3 (0.52) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229152-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2021-11-18 | — | — | WO | disclosed |