Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042545 | 0.82 | NAMPT (1.00) | NAMPT | |
| SCHEMBL24042598 | 0.79 | NAMPT (1.00) | NAMPT | |
| SCHEMBL23432009 | 0.78 | NAMPT (0.77) | NAMPT | |
| SCHEMBL23320451 | 0.73 | NAMPT (0.69) | NAMPT | |
| SCHEMBL20389421 | 0.73 | NAMPT (0.69) | NAMPT | |
| SCHEMBL20379901 | 0.72 | NAMPT (1.00) | NAMPT | |
| SCHEMBL24042535 | 0.72 | NAMPT (0.70) | NAMPT | |
| SCHEMBL20380306 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379639 | 0.71 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20389172 | 0.71 | NAMPT (0.66) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| US-20210361636-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361636-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | NAMPT, NME4, ABAT | NAMPT 1/4885PDE10A 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.