Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43231 | 0.87 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL20091594 | 0.84 | HPGD (0.33) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL8735537 | 0.81 | HPGD (0.37) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL3705350 | 0.79 | HDAC3 (0.44) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL24277969 | 0.79 | PSMB8 (0.30) | — | |
| SCHEMBL16453924 | 0.78 | HPGD (0.38) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL13001926 | 0.78 | HPGD (0.33) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL20091644 | 0.77 | HPGD (0.34) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL15669350 | 0.77 | SMN1; SMN2 (0.37) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL11913384 | 0.77 | SMN1; SMN2 (0.37) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912982-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | Hangzhou Dac Biotech Co., Ltd (CN) | 2021-11-24 | — | — | EP | disclosed |