SCHEMBL2404539

SCHEMBL2404539

O=C(OCCCCCCCOC(=O)c1ccc2c(c1)C(=O)OC2=O)c1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
HDAC6 Q9UBN7 1/20 0.49
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
ESR1 P03372 3/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406816 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2408748 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2408584 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2407617 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2405894 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2406569 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2407877 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL8967578 1.00 TDP1 (0.50) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2412690 0.98 TDP1 (0.51) TDP1HDAC6ALDH1A1MEN1KMT2A
SCHEMBL2404563 0.95 ALDH1A1 (0.48) TDP1HDAC6ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110210407-A1 DOUBLE-FACED ADHESIVE FILM AND ELECTRONIC COMPONENT MODULE USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-09-01 US disclosed
US-5571579-A FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM HITACHI CHEMICAL COMPANY, LTD (JP) 1996-11-05 US disclosed