Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820079 | 0.94 | ALDH1A1 (0.39) | ALDH1A1CHRM1 | |
| SCHEMBL2989371 | 0.92 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL2999757 | 0.90 | — | — | |
| SCHEMBL3000766 | 0.82 | — | — | |
| SCHEMBL3001670 | 0.81 | MAPT (0.32) | ALDH1A1CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL11667113 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL11812840 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL11812835 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL11882801 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C9TSHRCYP2C19TDP1 | |
| SCHEMBL24355161 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661925-B1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LTD (IE) | 2021-11-24 | — | — | EP | disclosed |