Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | QPCT | Q16769 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312653 | 0.77 | AR (0.63) | ESR1ESR2KMT2AMEN1ATM | |
| SCHEMBL24046890 | 0.76 | ABCB1 (0.60) | ADORA3KMT2AMEN1MAPTTP53 | |
| SCHEMBL311280 | 0.74 | HPGD (0.61) | QPCTKMT2AMEN1MAPTTP53 | |
| SCHEMBL311667 | 0.74 | CYP3A4 (0.61) | CSNK2A2CSNK2BCSNK2A1ESR2QPCT | |
| SCHEMBL312714 | 0.73 | TNKS (0.62) | ADORA3KMT2AMEN1MAPTTP53 | |
| SCHEMBL28568538 | 0.71 | CYP3A4 (0.72) | CSNK2A2CSNK2BCSNK2A1ADORA3KMT2A | |
| SCHEMBL13598259 | 0.70 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1ADORA3QPCT | |
| SCHEMBL24046861 | 0.70 | KDM4E (0.69) | CSNK2A2CSNK2BCSNK2A1KMT2AMEN1 | |
| SCHEMBL13479744 | 0.70 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1ADORA3QPCT | |
| SCHEMBL14749128 | 0.70 | MAPT (0.73) | CSNK2A2CSNK2BCSNK2A1ADORA3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |