Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | IP6K2 | Q9UHH9 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.73 |
| ▸ | TP53 | P04637 | 6/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.73 |
| ▸ | FLT3 | P36888 | 5/20 | 0.73 |
| ▸ | MAOA | P21397 | 5/20 | 0.73 |
| ▸ | MAOB | P27338 | 5/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675833 | 0.90 | ABCB1 (0.74) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| SCHEMBL1144261 | 0.90 | ABCB1 (0.74) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| SCHEMBL20868304 | 0.88 | MAPT (0.79) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| SCHEMBL15850944 | 0.87 | POLH (0.77) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| Apigenin SCHEMBL29351464 | 0.84 | KMT2A (1.00) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| Apigenin SCHEMBL5083245 | 0.84 | KMT2A (1.00) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| Apigenin SCHEMBL19428 | 0.84 | KMT2A (1.00) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| SCHEMBL20868306 | 0.84 | FTO (0.76) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| Apigenin SCHEMBL31168790 | 0.83 | KMT2A (0.97) | MAPTKMT2ACYP3A4MEN1KDM4E | |
| Apigenin SCHEMBL31477961 | 0.83 | KMT2A (0.97) | MAPTKMT2ACYP3A4MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITAET HAMBURG (DE) | 2019-04-04 | — | — | US | disclosed |
| US-9845482-B2 | Compositions and methods for enhancing bioenergetic status in female germ cells | THE GENERAL HOSPITAL CORPORATION (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140221319-A1 | Small Molecule CD38 Inhibitors and Methods of Using Same | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-08-07 | — | — | US | disclosed |
| US-20130059384-A1 | COMPOSITIONS AND METHODS FOR ENHANCING BIOENERGETIC STATUS IN FEMALE GERM CELLS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221319-A1 | Small Molecule CD38 Inhibitors and Methods of Using Same | CD38, CD22, CD2 | MAPT 3783/4885KMT2A 1089/4885CYP3A4 4737/4885 |
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | LRAT, TYR, CUTA | MAPT 846/4885KMT2A 2491/4885CYP3A4 1264/4885 |
| US-20130059384-A1 | COMPOSITIONS AND METHODS FOR ENHANCING BIOENERGETIC STATUS IN FEMALE GERM CELLS | PCK2, GSR, TFAM | MAPT 4110/4885KMT2A 2889/4885CYP3A4 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.