Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.64 |
| ▸ | TNKS | O95271 | 3/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046781 | 0.90 | CSNK2A2 (0.62) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL24046784 | 0.88 | CSNK2A2 (0.58) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL24046795 | 0.87 | TNKS (0.61) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL24046782 | 0.84 | CSNK2A2 (0.71) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL4160578 | 0.81 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| 7-Methoxyflavone SCHEMBL1373009 | 0.78 | TNKS (1.00) | TNKSCYP19A1CYP3A4KDM4EHPGD | |
| SCHEMBL24046914 | 0.78 | CSNK2A2 (0.76) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL24046783 | 0.77 | MAOB (0.55) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL29435863 | 0.76 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 | |
| SCHEMBL26117897 | 0.76 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1TNKSCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |