7-Methoxyflavone

7-Methoxyflavone

SCHEMBL1373009

COc1ccc2c(=O)cc(-c3ccccc3)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 3/20 1.00
CYP19A1 P11511 1/20 1.00
MAOB P27338 5/20 0.83
CYP3A4 P08684 7/20 0.81
KDM4E B2RXH2 6/20 0.81
ALDH1A1 P00352 6/20 0.81
HPGD P15428 5/20 0.81
HSD17B10 Q99714 5/20 0.81
SMN1; SMN2 Q16637 4/20 0.81
ABCB1 P08183 2/20 0.81
ABCG2 Q9UNQ0 1/20 0.81
USP2 O75604 1/20 0.81
MAPK1 P28482 1/20 0.81
RECQL P46063 1/20 0.81
MAPT P10636 5/20 0.74
TP53 P04637 5/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
CYP2C9 P11712 3/20 0.74
CYP2C19 P33261 3/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31238410 0.92 TNKS (0.84) TNKSCYP19A1MAOBCYP3A4KDM4E
4,7-Dimethoxyflavone SCHEMBL3470601 0.91 MAOB (1.00) TNKSCYP19A1MAOBCYP3A4KDM4E
7,3'-Dimethoxyflavone SCHEMBL718068 0.90 KDM4E (1.00) TNKSCYP19A1MAOBCYP3A4KDM4E
6-Methoxyflavone SCHEMBL312059 0.90 ABCB1 (1.00) TNKSCYP19A1MAOBCYP3A4KDM4E
6-Methoxyflavone SCHEMBL30799564 0.90 ABCB1 (1.00) TNKSCYP19A1MAOBCYP3A4KDM4E
6-Methoxyflavone SCHEMBL28930176 0.90 ABCB1 (1.00) TNKSCYP19A1MAOBCYP3A4KDM4E
6-Methoxyflavone SCHEMBL28301080 0.88 ABCB1 (0.97) TNKSCYP19A1MAOBCYP3A4KDM4E
SCHEMBL31238401 0.88 KDM4E (0.85) TNKSCYP19A1MAOBCYP3A4KDM4E
6-Methoxyflavone SCHEMBL27697051 0.86 ABCB1 (0.92) TNKSCYP19A1MAOBCYP3A4KDM4E
7-Methoxyflavone SCHEMBL28098795 0.86 TNKS (0.73) TNKSCYP19A1MAOBCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273610-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-09-01 US claimed
EP-4003016-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-06-01 EP claimed
WO-2021013930-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2021-01-28 WO claimed
EP-3769622-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2021-01-27 EP claimed
CN-106455665-A Fat or oil extract of black ginger and method for producing same 三得利控股株式会社 2017-02-22 CN claimed
US-20160361257-A1 COMPOSITION FOR INCREASING TESTOSTERONE LEVELS AND ENHANCING LIBIDO FARBER MICHAEL (US) 2016-12-15 US claimed
US-20160361258-A1 COMPOSITION FOR ENHANCING LIBIDO IN MAMMALS SMARTEK INTERNATIONAL, INC. 2016-12-15 US claimed
CN-106083793-A A kind of preparation method of 7 methoxy flavones 嘉兴学院 2016-11-09 CN claimed
CN-102993149-A Method for microwave-assisted synthesis of B-ring substituted flavone compound UNIV JIANGNAN 2013-03-27 CN claimed
US-20130030045-A1 METHOD OF PREVENTING AND TREATING OSTEOPOROSIS TSAI YU-HUI (TW) 2013-01-31 US claimed
CN-101914082-A Method for synthesizing 7-methoxyflavone HANGZHOU FST PHARMACEUTICAL CO LTD 2010-12-15 CN claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
EP-1109800-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LIMITED (KR) 2001-06-27 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
WO-2000012496-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LTD. (KR) 2000-03-09 WO claimed
US-5399584-A Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs THE PROCTER & GAMBLE COMPANY (US) 1995-03-21 US claimed
US-12594249-B2 Soluble curcumin and its derivatives THERMOLIFE INTERNATIONAL, LLC (US) 2026-04-07 US disclosed
US-5399584-A Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs THE PROCTER & GAMBLE COMPANY (US) 1995-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273610-A1 ANTIMYCOTIC ETF1, API5, ERG28 TNKS 2894/4885CYP19A1 2106/4885MAOB 1572/4885
US-12594249-B2 Soluble curcumin and its derivatives SLC2A8, SLC2A2, SLC2A1 TNKS 4705/4885CYP19A1 1268/4885MAOB 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.