Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.65 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046755 | 0.86 | CSNK2A2 (0.73) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL21801314 | 0.86 | CSNK2A2 (0.56) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL4649432 | 0.85 | CSNK2A2 (0.58) | CSNK2A2CSNK2BCSNK2A1CYP1A1CYP1A2 | |
| SCHEMBL4650589 | 0.85 | GABRP (0.61) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL24046998 | 0.82 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1TERT | |
| SCHEMBL24046894 | 0.82 | TNKS (0.56) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1B1 | |
| SCHEMBL24046752 | 0.80 | CSNK2A2 (0.78) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL24046750 | 0.80 | CSNK2A2 (0.63) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL24046757 | 0.80 | CSNK2A2 (0.60) | CSNK2A2CSNK2BCSNK2A1TERTKDM4E | |
| SCHEMBL24046990 | 0.80 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1TERTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |