Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046780 | 0.86 | ABCB1 (0.65) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8832339 | 0.84 | ABCB1 (0.65) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL24046875 | 0.83 | MAOB (0.60) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL29572571 | 0.77 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL1421511 | 0.77 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL29725288 | 0.77 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Trimethylapigenin SCHEMBL29350875 | 0.77 | ABCB1 (1.00) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Trimethylapigenin SCHEMBL1421585 | 0.77 | ABCB1 (1.00) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8833080 | 0.77 | ABCB1 (0.63) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16894667 | 0.76 | ABCB1 (0.74) | ABCB1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |