Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832339 | 0.90 | ABCB1 (0.65) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL1421511 | 0.79 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL29725288 | 0.79 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Tetramethylluteolin SCHEMBL29572571 | 0.79 | ABCB1 (0.80) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Trimethylapigenin SCHEMBL29350875 | 0.78 | ABCB1 (1.00) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| Trimethylapigenin SCHEMBL1421585 | 0.78 | ABCB1 (1.00) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16894667 | 0.78 | ABCB1 (0.74) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29978577 | 0.78 | ABCB1 (0.82) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL311530 | 0.78 | ABCB1 (0.82) | ABCB1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL24047003 | 0.77 | ABCB1 (0.61) | ABCB1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675023-A | VISION DEFECTS; NERVOUS SYSTEM DISORDERS; COMPLICATIONS OF DIABETES | TSUMURA & CO. (JP) | 1997-10-07 | — | — | US | disclosed |
| US-5627204-A | ENZYME INHIBITORS FOR TREATMENT OF DIABETES | TSUMURA & COMPANY (JP) | 1997-05-06 | — | — | US | disclosed |
| US-5455267-A | For reducing side effects of diabetes | TSUMURA & CO. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0516860-A1 | CHROMONE DERIVATIVE AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1992-12-09 | — | — | EP | disclosed |