Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25674225 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL9380087 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL9380090 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL8005742 | 0.81 | NPSR1 (0.46) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL12599765 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL22886614 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL14186862 | 0.76 | MAPT (0.53) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL1996045 | 0.75 | CA12 (0.66) | NLRP3CA12CA1CA2CA7 | |
| SCHEMBL1067165 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 | |
| SCHEMBL1067166 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303498-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
| US-20230303498-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | disclosed |
| WO-2021233787-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303498-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, DERL1, MTX1 | SMN1; SMN2 4034/4885NLRP3 4624/4885CA12 1113/4885 |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, CYP1B1, DERL1 | SMN1; SMN2 4042/4885NLRP3 4631/4885CA12 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.