Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2404800

CCCOC(=O)CC(O)C(=O)OCCC.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
DGKA P23743 1/20 0.36
ALDH1A1 P00352 4/20 0.36
HCAR2 Q8TDS4 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231276 0.98 NAAA (0.42) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL22303945 0.90 MGAM (0.43) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL511413 0.86 NAAA (0.53) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL20446066 0.86 NAAA (0.53) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL743529 0.86 NAAA (0.53) NAAAL3MBTL1MAPTMAPK1NPSR1
Ammonia Solution, Strong SCHEMBL31622513 0.85 NAAA (0.63) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL511411 0.84 NAAA (0.52) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL702876 0.84 NAAA (0.62) NAAAL3MBTL1MAPTMAPK1NPSR1
SCHEMBL1561849 0.83 SMN1; SMN2 (0.44) NAAADGKAALDH1A1HCAR2LMNA
SCHEMBL9099743 0.82 NAAA (0.66) NAAAL3MBTL1MAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011104555-A2 NOVEL PROCESS GENERICS [UK] LIMITED (GB) 2011-09-01 WO claimed
WO-2011104555-A2 NOVEL PROCESS GENERICS [UK] LIMITED (GB) 2011-09-01 WO disclosed