SCHEMBL2404847

SCHEMBL2404847

CCCCC(C(=O)C(C)O)=C(C#N)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.35
FNTB P49356 2/20 0.35
THRB P10828 1/20 0.35
PGGT1B P53609 1/20 0.35
CES1 P23141 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
CES2 O00748 1/20 0.32
FFAR1 O14842 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
AKR1B1 P15121 1/20 0.31
TP53 P04637 1/20 0.31
GPR84 Q9NQS5 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4470305 0.87 FNTA (0.39) FNTAFNTBTHRBPGGT1BCES1
SCHEMBL4475762 0.83 TP53 (0.31) TP53
SCHEMBL21525711 0.83 FNTA (0.45) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL21525719 0.81 FNTA (0.47) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL21525694 0.77 TP53 (0.33) FNTAFNTBTHRBPGGT1BTP53
SCHEMBL6440025 0.77 CES1 (0.39) FNTAFNTBTHRBPGGT1BCES1
SCHEMBL7546515 0.75 CES1 (0.45) FNTAFNTBTHRBPGGT1BCES1
SCHEMBL4470308 0.74 CES1 (0.33) CES1ALDH1A1CES2FFAR1FFAR4
SCHEMBL7546476 0.73 CES1 (0.41) CES1ALDH1A1CES2FFAR1FFAR4
SCHEMBL4475756 0.73 TP53 (0.31) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220025552-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) 2022-01-27 US claimed
EP-3894617-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2021-10-20 EP claimed
EP-3666940-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2020-06-17 EP claimed
EP-1317294-B2 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2009-09-02 EP claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
US-20220025552-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) 2022-01-27 US disclosed
EP-3894617-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2021-10-20 EP disclosed
EP-3666940-A1 METHOD OF PRODUCING POLY(ALKYL CYANOACRYLATE) BASED NANO/MICROFIBERS AND USES THEREOF Charité - Universitätsmedizin Berlin (DE) 2020-06-17 EP disclosed
EP-2366721-B1 Medical kit for use during negative pressure wound therapy AESCULAP AG (DE) 2016-08-10 EP disclosed
EP-2366721-A1 Medical kit for use during negative pressure wound therapy AESCULAP AG (DE) 2011-09-21 EP disclosed