Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475759 | 0.83 | TP53 (0.31) | TP53 | |
| SCHEMBL6440023 | 0.77 | CES1 (0.39) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL4470305 | 0.74 | FNTA (0.39) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL2404847 | 0.74 | FNTA (0.35) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL162501 | 0.72 | FNTA (0.46) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL18606215 | 0.70 | THRB (0.40) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL21525711 | 0.70 | FNTA (0.45) | FFAR1FFAR4AKR1B1ALDH1A1GPR84 | |
| SCHEMBL21525719 | 0.69 | FNTA (0.47) | FFAR1FFAR4ALDH1A1GPR84 | |
| SCHEMBL1274509 | 0.68 | CES1 (0.36) | CES1CES2FFAR1FFAR4AKR1B1 | |
| SCHEMBL1074445 | 0.67 | FNTA (0.53) | CES1CES2FFAR1FFAR4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317294-B2 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2009-09-02 | — | — | EP | claimed |
| EP-1317294-B1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2005-03-16 | — | — | EP | claimed |