Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404883 | 1.00 | HDAC6 (0.63) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL7935105 | 0.88 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2403223 | 0.88 | HDAC6 (0.76) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2403216 | 0.88 | HDAC6 (0.76) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2404957 | 0.86 | HDAC6 (0.57) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2404960 | 0.79 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2404962 | 0.79 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL1421158 | 0.79 | HDAC6 (0.74) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2402959 | 0.78 | HDAC1 (0.62) | HDAC6HDAC3HDAC1HDAC8HDAC5 | |
| SCHEMBL2402966 | 0.78 | HDAC1 (0.62) | HDAC6HDAC3HDAC1HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | HDAC6 8/4885HDAC3 10/4885HDAC1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.