SCHEMBL2404932

SCHEMBL2404932

NC1=Cc2ccccc2C(C(=O)O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 5/20 0.40
EDNRB P24530 4/20 0.40
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
HBB P68871 1/20 0.34
GRM1 Q13255 2/20 0.33
GRM2 Q14416 1/20 0.33
GRM4 Q14833 1/20 0.33
ATM Q13315 1/20 0.33
LMNA P02545 2/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
THRB P10828 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15104959 0.82 EDNRA (0.36) EDNRAEDNRBCYP2D6MAPTALOX15
SCHEMBL27970746 0.81 EDNRA (0.38) EDNRAEDNRBMAPTALOX15GRM1
SCHEMBL27925789 0.81 EDNRA (0.35) EDNRAEDNRBCYP2D6MAPTALOX15
SCHEMBL5404798 0.79 EDNRA (0.34) EDNRAEDNRBCYP2D6MAPTALOX15
SCHEMBL31213694 0.79 EDNRA (0.34) EDNRAEDNRBCYP2D6MAPTALOX15
SCHEMBL2400874 0.74 EDNRA (0.37) EDNRAEDNRBALOX15ATMLMNA
SCHEMBL30522434 0.74 EDNRA (0.37) EDNRAEDNRBATMLMNAALDH1A1
SCHEMBL8797292 0.72 HTR2A (0.43) EDNRAEDNRBCYP2D6ATMLMNA
SCHEMBL129881 0.70 CYP2D6 (0.44) EDNRAEDNRBCYP2D6MAPTALOX15
SCHEMBL31379445 0.70 CYP2D6 (0.44) EDNRAEDNRBCYP2D6MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed