SCHEMBL2405229

SCHEMBL2405229

Nc1ccc(C2(N)C=CC(N)(N)C=C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 8/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
OPRK1 P41145 1/20 0.35
CYP3A4 P08684 5/20 0.35
TDP1 Q9NUW8 4/20 0.35
TP53 P04637 1/20 0.35
NSD2 O96028 1/20 0.34
APP P05067 2/20 0.32
MASP2 O00187 1/20 0.32
PLAU P00749 1/20 0.32
THPO P40225 1/20 0.32
ALOX15 P16050 2/20 0.32
MAPK1 P28482 2/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11857865 0.64 MEN1 (0.80) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL14082287 0.63 ALDH1A1 (0.52) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL22500166 0.63
SCHEMBL320609 0.63 MEN1 (1.00) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL27981 0.63
SCHEMBL14292398 0.60 ALDH1A1 (0.54) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL5886235 0.60 ALDH1A1 (0.56) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL940896 0.60 ALDH1A1 (0.76) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL1652426 0.60
SCHEMBL21749649 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646899-B n-type semiconductor element, method for manufacturing n-type semiconductor element, wireless communication device, and commodity tag 东丽株式会社 2024-03-12 CN disclosed
WO-2023171705-A1 METHOD FOR MANUFACTURING SINGLE-SIDE METAL-CLAD LAYERED PLATE 株式会社カネカ 2023-09-14 WO disclosed
CN-111128548-A Composite solid-state capacitor and method for manufacturing same 钰冠科技股份有限公司 2020-05-08 CN disclosed
US-20130065227-A1 METHODS OF INCREASING MACROPINOCYTOSIS IN CANCER CELLS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2013-03-14 US disclosed
WO-2011109677-A2 METHODS OF INCREASING MACROPINOCYTOSIS IN CANCER CELLS UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2011-09-09 WO disclosed