2,6-Diaminopurine

2,6-Diaminopurine

SCHEMBL24053

Nc1nc(N)c2[nH]cnc2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 1.00
GDA Q9Y2T3 1/20 1.00
CDK2 P24941 11/20 0.66
DPP4 P27487 1/20 0.66
MAP3K5 Q99683 1/20 0.59
PI4KA P42356 2/20 0.55
PI4K2B Q8TCG2 2/20 0.55
PI4K2A Q9BTU6 2/20 0.55
PI4KB Q9UBF8 2/20 0.55
LMNA P02545 1/20 0.55
DRD3 P35462 1/20 0.55
XDH P47989 1/20 0.55
LRRK2 Q5S007 1/20 0.55
CDK1 P06493 10/20 0.54
CCNB1 P14635 10/20 0.54
CCNA2 P20248 10/20 0.54
CCNA1 P78396 10/20 0.54
MGMT P16455 3/20 0.51
ADORA2A P29274 1/20 0.51
ADORA1 P30542 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Diaminopurine SCHEMBL28206545 0.98 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL27891733 0.98 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL8757979 0.98 PDPK1 (0.96) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL29143272 0.96 PDPK1 (0.92) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL1033682 0.91 PDPK1 (0.82) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL30680639 0.89 PDPK1 (0.79) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL13857840 0.89 PDPK1 (0.79) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL4535059 0.89 PDPK1 (0.79) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL3238169 0.89 PDPK1 (0.79) PDPK1GDACDK2DPP4MAP3K5
2,6-Diaminopurine SCHEMBL28083713 0.89 PDPK1 (0.79) PDPK1GDACDK2DPP4MAP3K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 66527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260146273-A1 METHOD FOR ONE-POT BIOSYNTHESIS OF ARABINONUCLEOSIDE, AND COMPOSITION ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) 2026-05-28 US claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
US-20260124274-A1 METHODS OF INCREASING READTHROUGH OF A PREMATURE TERMINATION CODON UNIV RAMOT (IL) 2026-05-07 US claimed
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-20260117285-A1 COMPOSITIONS AND METHODS FOR IMPROVING LIBRARY ENRICHMENT ILLUMINA INC (US) 2026-04-30 US claimed
WO-2026090528-A2 CIRCULARLY STRUCTURED GUIDE RNAS FOR CRISPR GENOME EDITING UNIVERSITY OF MASSACHUSETTS (US) 2026-04-30 WO claimed
US-20260117116-A1 COMPOSITION AND METHOD FOR HYDRAULIC FRACTURING AND EVALUATION AND DIAGNOSTICS OF HYDRAULIC FRACTURES USING INFUSED POROUS CERAMIC PROPPANT CARBO CERAMICS INC (US) 2026-04-30 US claimed
WO-1988004301-A1 alpha OLIGONUCLEOTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1988-06-16 WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed
EP-0254268-A2 Fluorinated nucleosides,their preparation and their pharmaceutical use against AIDS THE WELLCOME FOUNDATION LIMITED (GB) 1988-01-27 EP claimed
EP-0117777-B1 COMPOUNDS CONTAINING AN OLIGONUCLEOTIDE BONDED TO AN INTERCALLATING AGENT, A PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1987-12-23 EP claimed
US-4670424-A Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides MERCK & CO., INC. (US) 1987-06-02 US claimed
EP-0214908-A1 Compounds containing an oligonucleotide sequence linked to an intercalating agent and to an activable chemical group, their synthesis and applications to artificial sequence-specific nucleases CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1987-03-18 EP claimed
WO-1986003678-A1 COMPOSITION AND METHOD FOR TREATMENT OF TUMORS WITH UDPG MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (US) 1986-07-03 WO claimed
EP-0169787-A1 Use of oligonucleotides bonded to an intercalating agent as drugs CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-01-29 EP claimed
EP-0138656-A1 Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides, their preparation and their application in anti-viral compositions MERCK & CO. INC. (US) 1985-04-24 EP claimed
US-4002532-A BINDING ANTIBODIES WELTMAN JOEL K 1977-01-11 US claimed