SCHEMBL24055232

SCHEMBL24055232

O=c1[nH]cnc2c1oc1ccc(-c3cccc(-c4ccc(-c5ccccc5)cc4)c3)cc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.66
PIM1 P11309 4/20 0.64
PIM3 Q86V86 3/20 0.64
PIM2 Q9P1W9 3/20 0.64
CDC7 O00311 2/20 0.64
CSNK2A1 P68400 2/20 0.64
CSNK2A2 P19784 2/20 0.64
CSNK2B P67870 2/20 0.64
IGF1R P08069 2/20 0.64
CLK2 P49760 2/20 0.64
GSK3A P49840 2/20 0.64
GSK3B P49841 2/20 0.64
DYRK1A Q13627 2/20 0.64
CLK4 Q9HAZ1 2/20 0.64
CSNK2A3 Q8NEV1 1/20 0.64
DYRK3 O43781 1/20 0.64
PKN2 Q16513 1/20 0.64
PLA2G2A P14555 4/20 0.44
PLA2G4A P47712 4/20 0.44
PLA2G10 O15496 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31110304 1.00 KDM4E (0.66) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL23610610 0.97 KDM4E (0.69) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL22126620 0.84 KDM4E (0.62) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL27164736 0.84 KDM4E (0.58) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL1857738 0.80 KDM4E (1.00) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL12661345 0.78 PIM1 (1.00) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL18496527 0.78 PIM1 (0.70) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL4594776 0.78 PIM1 (0.70) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL4594347 0.78 PIM1 (1.00) KDM4EPIM1PIM3PIM2CDC7
SCHEMBL27164741 0.77 KDM4E (0.76) KDM4EPIM1PIM3PIM2CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210363151-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210363151-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device AHR, CYP1A1, ARNT KDM4E 2083/4885PIM1 2569/4885PIM3 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.