SCHEMBL2405656

SCHEMBL2405656

N=C=O.O=C=NCCCCN=C=O

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
BACH1 O14867 1/20 0.30
MAFK O60675 1/20 0.30
EGFR P00533 1/20 0.30
PTGS2 P35354 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289205 1.00 MIF (0.30) MIFALDH1A1LMNATP53BACH1
SCHEMBL29161887 0.97 NAAA (0.33) MIF
SCHEMBL28344380 0.97 NAAA (0.33) MIF
SCHEMBL1246899 0.97 NAAA (0.33) MIF
SCHEMBL9315987 0.97 NAAA (0.33) MIF
SCHEMBL482838 0.97 NAAA (0.33) MIF
SCHEMBL5444944 0.97 NAAA (0.33) MIF
SCHEMBL7626800 0.97 NAAA (0.33) MIF
SCHEMBL1582244 0.97 NAAA (0.33) MIF
Methane SCHEMBL22150430 0.94 NAAA (0.32) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679013-B1 METHOD FOR MAKING ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-11-29 EP disclosed
US-8981145-B2 Process for preparing isocyanates BASF SE (DE) 2015-03-17 US disclosed
US-20110230676-A1 PROCESS FOR PREPARING ISOCYANATES BASF SE (DE) 2011-09-22 US disclosed
US-7702257-B2 Image forming apparatus with image bearing member having a lubricant RICOH COMPANY LIMITED (JP) 2010-04-20 US disclosed
EP-1510879-A1 Image forming apparatus and process cartridge Ricoh Company (JP) 2005-03-02 EP disclosed