SCHEMBL24057488

SCHEMBL24057488

c1ccc(-c2ccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3ccc(-c4ccc5c(n4)oc4ccccc45)cc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.37
CYP1B1 Q16678 2/20 0.37
TBK1 Q9UHD2 1/20 0.35
PGR P06401 1/20 0.35
CYP1A2 P05177 4/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
ESR1 P03372 3/20 0.33
ESR2 Q92731 3/20 0.33
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25662867 0.98 ESR1 (0.35) CYP1A1CYP1B1TBK1CYP1A2SMN1; SMN2
SCHEMBL26833920 0.96 CYP1A1 (0.34) CYP1A1CYP1B1TBK1PGRCYP1A2
SCHEMBL25662868 0.94 GRM4 (0.32) CYP1A1CYP1B1TBK1PGRCYP1A2
SCHEMBL25662908 0.94 CYP1A1 (0.34) CYP1A1CYP1B1CYP1A2SMN1; SMN2ALDH1A1
SCHEMBL26833938 0.93 CYP1A1 (0.32) CYP1A1CYP1B1CYP1A2KMT2ASMN1; SMN2
SCHEMBL26833932 0.92 CYP1A1 (0.34) CYP1A1CYP1B1CYP1A2KMT2ASMN1; SMN2
SCHEMBL26834088 0.92 TBK1 (0.34) TBK1PGRKMT2AALDH1A1KDM4E
SCHEMBL26833707 0.92 CYP1A1 (0.33) CYP1A1CYP1B1CYP1A2KMT2ASMN1; SMN2
SCHEMBL25662865 0.92 MAPK1 (0.34) CYP1A1CYP1B1TBK1PGRKMT2A
SCHEMBL24057196 0.92 TBK1 (0.34) CYP1B1TBK1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
WO-2021235906-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2021-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR0B1, AHR, ARL1 CYP1A1 10/4885CYP1B1 63/4885TBK1 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.