Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667150 | 0.86 | CYP2A6 (0.39) | POLRMTDOT1LMAP4K4TNIKSTING1 | |
| SCHEMBL4970560 | 0.86 | CYP2A6 (0.39) | POLRMTDOT1LMAP4K4TNIKSTING1 | |
| SCHEMBL19344220 | 0.86 | CYP2A6 (0.39) | POLRMTDOT1LMAP4K4TNIKSTING1 | |
| SCHEMBL19344234 | 0.86 | CYP2A6 (0.39) | POLRMTDOT1LMAP4K4TNIK | |
| SCHEMBL20834955 | 0.84 | DOT1L (0.35) | POLRMTDOT1LMAP4K4STING1 | |
| SCHEMBL24340458 | 0.81 | POLRMT (0.43) | POLRMTDOT1L | |
| SCHEMBL22355531 | 0.81 | POLRMT (0.43) | POLRMTDOT1L | |
| SCHEMBL24606310 | 0.81 | DOT1L (0.36) | POLRMTDOT1L | |
| SCHEMBL24606327 | 0.80 | DOT1L (0.34) | POLRMTDOT1L | |
| SCHEMBL23584543 | 0.80 | MAP4K4 (0.36) | POLRMTDOT1LMAP4K4STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212175-B1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES INC (US) | 2021-11-24 | — | — | EP | disclosed |