Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | POLD1 | P28340 | 1/20 | 0.58 |
| ▸ | TYMS | P04818 | 1/20 | 0.52 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18184311 | 0.87 | POLB (0.74) | TK1POLBTYMS | |
| SCHEMBL8389089 | 0.87 | POLB (0.74) | TK1POLBTYMS | |
| SCHEMBL14279193 | 0.87 | POLB (0.74) | TK1POLBTYMS | |
| SCHEMBL24593487 | 0.87 | POLB (0.74) | TK1POLBTYMS | |
| SCHEMBL18184310 | 0.87 | TK1 (0.58) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL20857214 | 0.86 | TK1 (0.65) | TK1POLBPOLA1POLD1RNASE1 | |
| SCHEMBL19227506 | 0.85 | TK1 (0.68) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL22541148 | 0.85 | POLB (0.70) | TK1POLBTYMS | |
| SCHEMBL27062483 | 0.85 | TK1 (0.68) | TK1POLBPOLA1POLD1TYMS | |
| SCHEMBL18119004 | 0.84 | TK1 (0.59) | TK1POLBPOLA1POLD1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |