⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477597 | 0.83 | — | — | |
| SCHEMBL924925 | 0.80 | — | — | |
| SCHEMBL6124720 | 0.79 | — | — | |
| SCHEMBL22832982 | 0.79 | — | — | |
| SCHEMBL2178792 | 0.76 | — | — | |
| SCHEMBL2677801 | 0.72 | PPM1D (0.32) | — | |
| SCHEMBL6124719 | 0.71 | — | — | |
| SCHEMBL18763674 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL18763672 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL17327314 | 0.68 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |