SCHEMBL2406049

SCHEMBL2406049

O=C(O)C(=C(C(=O)O)C(F)C(F)F)C(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3230539 0.73
SCHEMBL377875 0.72
Fluoride SCHEMBL29178590 0.69
SCHEMBL1006667 0.69
SCHEMBL7828774 0.67
Bicarbonate SCHEMBL29184123 0.65 CA1 (0.31)
SCHEMBL1646253 0.65
SCHEMBL3805961 0.65
SCHEMBL2069150 0.62 ALDH1A1 (0.40)
SCHEMBL25362966 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62106432-A None JP disclosed
JP-62099720-A None JP disclosed
US-20140142095-A1 AGENTS USEFUL FOR TREATING FRIEDREICH'S ATAXIA AND OTHER NEURODEGENERATIVE DISEASES SERKET PHARMA, LLC (US) 2014-05-22 US disclosed
US-8012658-B2 binder resin including a polyester resin and a vinyl resin which the monomer having an alkyloxysilyl group, a wax and a colors; good fixability, durability, noncracking during high speed recording without causing the offset problem RICOH COMPANY LIMITED (JP) 2011-09-06 US disclosed
US-7829254-B2 Non-magnetic toner, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-09 US disclosed
US-20080220357-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGE, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE TONER RICOH COMPANY LIMITED (JP) 2008-09-11 US disclosed
US-20070218388-A1 NON-MAGNETIC TONER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed
US-5391589-A Graft polymerizing a hydrophilic monomer onto a surface radiated substrate; uniformily crosslinking; permanent surface wettability; good wearability SEIKO EPSON CORPORATION (JP) 1995-02-21 US disclosed
US-4868260-A OXYGEN PERMEABILITY TOMEI SANGYO KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
JP-S62106432-A CONTACT LENS MATERIAL TOOMEE SANGYO KK 1987-05-16 JP disclosed
JP-S6299720-A CONTACT LENS MATERIAL TOOMEE SANGYO KK 1987-05-09 JP disclosed