Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473286 | 1.00 | KDM1A (0.37) | KDM1AKCNH2PRCPCA1TSHR | |
| SCHEMBL2708040 | 1.00 | KDM1A (0.37) | KDM1AKCNH2PRCPCA1TSHR | |
| SCHEMBL12980157 | 1.00 | KDM1A (0.37) | KDM1AKCNH2PRCPCA1TSHR | |
| SCHEMBL6121504 | 1.00 | KDM1A (0.37) | KDM1AKCNH2PRCPCA1TSHR | |
| SCHEMBL2708049 | 1.00 | KDM1A (0.37) | KDM1AKCNH2PRCPCA1TSHR | |
| Hydrochloric Acid SCHEMBL2708312 | 0.98 | KDM1A (0.39) | KDM1AKCNH2PRCPCA1TSHR | |
| SCHEMBL3943919 | 0.82 | HTR3A (0.41) | KDM1APRCPSLC6A3 | |
| SCHEMBL13744292 | 0.81 | SLC18A3 (0.39) | PRCP | |
| SCHEMBL5054915 | 0.81 | SLC18A3 (0.39) | PRCP | |
| SCHEMBL24365527 | 0.81 | SLC18A3 (0.39) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601273-B1 | 4-PIPERIDIN-N-(PYRIMIDIN-4-YL)CHROMAN-7-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | GENENTECH INC (US) | 2021-12-01 | — | — | EP | disclosed |