Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263815 | 0.85 | HSD17B10 (0.54) | HSD17B10GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4347112 | 0.83 | HSD17B10 (0.52) | HSD17B10GAAL3MBTL1 | |
| SCHEMBL2406139 | 0.78 | HSD17B10 (0.42) | HSD17B10GAA | |
| Piperidine SCHEMBL11714957 | 0.64 | — | — | |
| Piperidine SCHEMBL10008663 | 0.64 | ALDH1A1 (0.82) | ALDH1A1 | |
| SCHEMBL11508384 | 0.64 | ALDH1A1 (1.00) | ALDH1A1GAA | |
| SCHEMBL8253733 | 0.64 | ALDH1A1 (1.00) | ALDH1A1GAA | |
| Piperidine SCHEMBL8435190 | 0.64 | ALDH1A1 (1.00) | ALDH1A1GAA | |
| SCHEMBL21753221 | 0.64 | ALDH1A1 (1.00) | ALDH1A1GAA | |
| Piperidine SCHEMBL21819962 | 0.64 | ALDH1A1 (1.00) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651917-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| EP-2651919-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012080271-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080260-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |