Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.57 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24061553 | 0.90 | BTK (0.57) | BTKLCK | |
| SCHEMBL24061699 | 0.86 | BTK (0.47) | BTK | |
| SCHEMBL17645885 | 0.84 | BTK (0.78) | BTKLCK | |
| SCHEMBL24061690 | 0.82 | BTK (0.51) | BTKLCK | |
| SCHEMBL17645882 | 0.81 | BTK (0.79) | BTKLCK | |
| SCHEMBL27457324 | 0.79 | BTK (0.53) | BTKLCK | |
| SCHEMBL24061705 | 0.79 | BTK (0.58) | BTKLCK | |
| SCHEMBL17645666 | 0.78 | BTK (0.63) | BTKLCK | |
| SCHEMBL17646036 | 0.77 | BTK (0.59) | BTKLCK | |
| SCHEMBL17645888 | 0.77 | BTK (0.73) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |