SCHEMBL2406352

SCHEMBL2406352

CC1C=C(C(=O)Oc2cccc3cccc(OC(=O)c4ccccc4)c23)CCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KMT2A Q03164 9/20 0.40
STAT3 P40763 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPT P10636 4/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 3/20 0.39
HSD17B10 Q99714 2/20 0.39
JAK2 O60674 1/20 0.39
USP2 O75604 1/20 0.39
ESR1 P03372 1/20 0.39
GAA P10253 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403641 0.91 KMT2A (0.43) LMNAMETAP2METAP1HDAC6KMT2A
SCHEMBL2403746 0.89 KMT2A (0.45) LMNAKMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL2402673 0.85 KMT2A (0.44) LMNAKMT2ACYP2C9CYP2C19MAPT
SCHEMBL18035757 0.84 HSD17B10 (0.40) LMNAALDH1A1CYP1A2CYP2C9MAPT
SCHEMBL2403661 0.79 LMNA (0.46) LMNAMETAP2METAP1HDAC6KMT2A
SCHEMBL2404510 0.79 LMNA (0.41) LMNAMETAP2METAP1HDAC6KMT2A
SCHEMBL18035722 0.78 MYC (0.38) LMNAKMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL2402734 0.78 LMNA (0.41) LMNAMETAP2METAP1HDAC6KMT2A
SCHEMBL18035785 0.78
SCHEMBL12355077 0.78 KMT2A (0.61) LMNAMETAP2METAP1HDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US claimed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US disclosed