Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688498 | 0.89 | HPGD (0.44) | GAAALDH1A1LMNANPC1TDP1 | |
| SCHEMBL21082486 | 0.78 | GAA (0.44) | GAAABCB1HTR3EHTR3BCHRNA7 | |
| SCHEMBL14853745 | 0.77 | GAA (0.43) | GAAABCB1ALDH1A1LMNANPC1 | |
| SCHEMBL4284269 | 0.75 | ABCB1 (0.45) | GAAABCB1ALDH1A1 | |
| SCHEMBL16063068 | 0.74 | ABCB1 (0.41) | GAAABCB1ALDH1A1LMNA | |
| SCHEMBL21082360 | 0.74 | LMNA (0.45) | GAACHRNA7ALDH1A1LMNANPC1 | |
| SCHEMBL14853753 | 0.73 | ABCB1 (0.45) | GAAABCB1ALDH1A1 | |
| SCHEMBL23409157 | 0.73 | HPGD (0.39) | ABCB1ALDH1A1NPC1 | |
| SCHEMBL26290153 | 0.73 | LMNA (0.44) | GAACHRNA7ALDH1A1LMNANPC1 | |
| SCHEMBL4283219 | 0.72 | ABCB1 (0.44) | GAAABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682905-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2021-12-01 | — | — | EP | disclosed |