Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23341894 | 0.86 | HDAC4 (0.48) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL10017160 | 0.83 | IDO1 (0.54) | ALDH1A1HPGDBCL2L1HSD17B10ACHE | |
| SCHEMBL29511656 | 0.82 | ACHE (0.45) | ALDH1A1HPGDBCL2L1HSD17B10MAPT | |
| SCHEMBL15128905 | 0.82 | ACHE (0.45) | ALDH1A1HPGDBCL2L1HSD17B10MAPT | |
| SCHEMBL24936787 | 0.81 | BCL2L1 (0.46) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL27979829 | 0.81 | HPGD (0.60) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL7918998 | 0.80 | MAPT (0.47) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL23341325 | 0.78 | HDAC4 (0.42) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL25957743 | 0.78 | ACHE (0.45) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL26482166 | 0.77 | MCL1 (0.43) | HDAC8HDAC6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3373353-B1 | ORGANIC LIGHT-EMITTING ELEMENT | LG CHEMICAL LTD (KR) | 2021-12-01 | — | — | EP | disclosed |