SCHEMBL2406463

SCHEMBL2406463

N=C(N)C1CCCCCC1

nearest known ligand 0.94

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 11/20 0.94
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
MGLL Q99685 1/20 0.38
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
CTSK P43235 1/20 0.35
EPHX1 P07099 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
F2 P00734 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18557034 1.00 NOS2 (0.94) NOS2CES2CES1NOS3NOS1
SCHEMBL8297591 1.00 NOS2 (0.94) NOS2CES2CES1NOS3NOS1
SCHEMBL18557010 1.00 NOS2 (0.94) NOS2CES2CES1NOS3NOS1
SCHEMBL8297589 1.00 NOS2 (0.94) NOS2CES2CES1NOS3NOS1
SCHEMBL351674 1.00
SCHEMBL172486 1.00 NOS2 (0.94) NOS2CES2CES1NOS3NOS1
Hydrochloric Acid SCHEMBL4776722 0.97 NOS2 (0.88) NOS2CES2CES1NOS3NOS1
Hydrochloric Acid SCHEMBL4779768 0.97 NOS2 (0.88) NOS2CES2CES1NOS3NOS1
Hydrochloric Acid SCHEMBL908978 0.97 NOS2 (0.88) NOS2CES2CES1NOS3NOS1
Water SCHEMBL28658762 0.97 NOS2 (0.88) NOS2CES2CES1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4522763-A STARTING MATERIALS FOR CROP PROTECTION AGENTS AND SELECTIVE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US claimed
EP-2539327-A1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE Piramal Enterprises Limited (IN) 2013-01-02 EP disclosed
WO-2011104680-A1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-09-01 WO disclosed
US-4522763-A STARTING MATERIALS FOR CROP PROTECTION AGENTS AND SELECTIVE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US disclosed
EP-0073442-B1 N-ALKOXYCARBONYL AND N-ALKOXYTHIOCARBONYL AMIDINES AND PREPARATION THEREOF BASF Aktiengesellschaft (DE) 1985-03-13 EP disclosed
EP-0073442-A2 N-alkoxycarbonyl and N-alkoxythiocarbonyl amidines and preparation thereof BASF Aktiengesellschaft (DE) 1983-03-09 EP disclosed