Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590555 | 0.87 | TSHR (0.52) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL30471377 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL31572063 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL27947144 | 0.84 | TSHR (0.53) | TSHRTHRB | |
| SCHEMBL486995 | 0.84 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL27973525 | 0.84 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL6032005 | 0.84 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Chloromethane SCHEMBL27919857 | 0.82 | TSHR (0.81) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Octane SCHEMBL9281542 | 0.82 | TSHR (0.50) | TSHRTHRB | |
| Chloromethane SCHEMBL27565490 | 0.82 | TSHR (0.81) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479599-B2 | Antibodies against SARS-CoV-2 and methods of using the same | Vir Biotechnology, Inc. (US) | 2022-10-25 | — | — | US | disclosed |
| US-20210371504-A1 | ANTIBODIES AGAINST SARS-COV-2 AND METHODS OF USING THE SAME | Vir Biotechnology, Inc. | 2021-12-02 | — | — | US | disclosed |