Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329052 | 0.80 | APP (0.46) | LMNATP53BLMCA1 | |
| SCHEMBL28621315 | 0.78 | APP (0.44) | LMNATP53BLMCA1 | |
| Ammonia Solution, Strong SCHEMBL18008289 | 0.78 | APP (0.44) | LMNATP53BLMCA1 | |
| SCHEMBL19958498 | 0.78 | PMP22 (0.43) | LMNABLMPMP22 | |
| SCHEMBL966471 | 0.78 | APP (0.44) | LMNATP53BLMCA1 | |
| SCHEMBL223999 | 0.75 | LMNA (0.38) | LMNABLM | |
| Dimethylamine SCHEMBL18008742 | 0.74 | APP (0.41) | LMNATP53BLMCA1 | |
| SCHEMBL17369606 | 0.74 | LMNA (0.41) | LMNATP53BLMCA1 | |
| SCHEMBL5637565 | 0.73 | APP (0.44) | LMNATP53BLMCA1 | |
| SCHEMBL10045748 | 0.73 | LMNA (0.54) | LMNATP53BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242849-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | THE ROCKEFELLER UNIVERSITY (US) | 2021-12-02 | — | — | WO | disclosed |