SCHEMBL24065337

SCHEMBL24065337

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5ccc6c7cccc(-c8ccccc8)c7sc6c54)n3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 1/20 0.38
▸ DUSP3 P51452 1/20 0.34
▸ MAPK14 Q16539 1/20 0.33
▸ ALOX5 P09917 1/20 0.32
▸ ATM Q13315 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745473 0.98 LIMK1 (0.39) LIMK1DUSP3MAPK14ALOX5ATM
SCHEMBL25585483 0.92 L3MBTL1 (0.38) LIMK1DUSP3MAPK14ALOX5ATM
SCHEMBL25585599 0.92 LIMK1 (0.37) LIMK1DUSP3MAPK14ALOX5ATM
SCHEMBL25585502 0.92 L3MBTL1 (0.38) LIMK1DUSP3MAPK14ALOX5ATM
SCHEMBL24209984 0.92 ATM (0.32) LIMK1DUSP3MAPK14ATMKDM4E
SCHEMBL24210214 0.92 ATM (0.32) LIMK1DUSP3MAPK14ATMKDM4E
SCHEMBL24417357 0.91 LIMK1 (0.36) LIMK1DUSP3MAPK14ALOX5ALDH1A1
SCHEMBL24417265 0.91 LIMK1 (0.36) LIMK1DUSP3MAPK14ALOX5ALDH1A1
SCHEMBL24417319 0.91 LIMK1 (0.36) LIMK1DUSP3MAPK14ALOX5ALDH1A1
SCHEMBL25585481 0.91 L3MBTL1 (0.39) LIMK1DUSP3MAPK14ALOX5ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119201-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-04-20 — — US disclosed
US-20220149289-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-05-12 — — US disclosed
US-20220006029-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-01-06 — — US disclosed
US-20210380534-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-12-09 — — US disclosed
US-20210376245-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-12-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380534-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OCIAD2, OSTC LIMK1 135/4885DUSP3 2886/4885MAPK14 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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