Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111641 | 0.85 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL17111612 | 0.76 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL18792218 | 0.71 | NTRK1 (0.71) | NTRK1 | |
| SCHEMBL17111840 | 0.70 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL25747881 | 0.70 | NTRK1 (0.72) | NTRK1 | |
| SCHEMBL18792167 | 0.69 | NTRK1 (0.75) | NTRK1 | |
| SCHEMBL18762396 | 0.67 | NTRK1 (0.56) | NTRK1 | |
| SCHEMBL22213379 | 0.66 | NTRK1 (0.73) | NTRK1 | |
| SCHEMBL17111815 | 0.65 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL18786528 | 0.64 | NTRK1 (0.52) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371399-A1 | TrkA Inhibitor | ELI LILLY AND COMPANY | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371399-A1 | TrkA Inhibitor | NGF, NGFR, OPRL1 | NTRK1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.