Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065915 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL16815043 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL16812856 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL24065914 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL24065979 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL8260150 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL17977269 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL7434354 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL7436135 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL7430439 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHPGDPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814452-B2 | Aziridine polymers whose chemical structural changes are induced by mechanical force | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-11-14 | — | — | US | disclosed |
| US-11814452-B2 | Aziridine polymers whose chemical structural changes are induced by mechanical force | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-11-14 | — | — | US | disclosed |
| US-20210371557-A1 | AZIRIDINE POLYMERS WHOSE CHEMICAL STRUCTURAL CHANGES ARE INDUCED BY MECHANICAL FORCE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2021-12-02 | — | — | US | disclosed |