Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24068077 | 0.90 | MEN1 (0.33) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24068172 | 0.81 | KDM4E (0.32) | ALDH1A1MAPTCYP3A4KDM4ELMNA | |
| SCHEMBL24068092 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL25730229 | 0.76 | RXRA (0.31) | — | |
| SCHEMBL25730386 | 0.75 | — | — | |
| SCHEMBL24068093 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24068062 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL25280670 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24068175 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL30339111 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667257-B | Compounds for inhibiting CDK7 | 伊莱利利公司 | 2024-06-11 | — | — | CN | disclosed |
| US-20230203031-A1 | COMPOUNDS USEFUL FOR INHIBITING CDK7 | ELI LILLY AND COMPANY | 2023-06-29 | — | — | US | disclosed |
| US-20230203031-A1 | COMPOUNDS USEFUL FOR INHIBITING CDK7 | ELI LILLY AND COMPANY | 2023-06-29 | — | — | US | disclosed |
| EP-4157840-A1 | COMPOUNDS USEFUL FOR INHIBITING CDK7 | Eli Lilly and Company (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-115667257-A | Compounds for inhibiting CDK7 | 伊莱利利公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021242602-A1 | COMPOUNDS USEFUL FOR INHIBITING CDK7 | ELI LILLY AND COMPANY (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203031-A1 | COMPOUNDS USEFUL FOR INHIBITING CDK7 | CDK7, CDK3, CCNH | SMN1; SMN2 2349/4885ALDH1A1 3476/4885NPC1 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.